Career Opportunities

You will lead our strategic planning process in Technology and create and maintain strategic alignment between priorities and the needs with stakeholders across Science, including our scientific leaders across the Biohub network. You'll be a strategic thought partner for the Head of Technology in Science.

You will be responsible for ensuring end-to-end delivery of the imaging datasets, first to AI researchers, and ultimately to the scientific community. You will partner with research scientists, engineers, and data scientists to design and implement systems to acquire, transform, store, manage, and prepare data for model training. You will ensure the system implements requirements from Product Management to make those data useful and accessible for the scientific community. You will ensure data we create are standardized and carry uniform metadata–across imaging modalities but also across other data types we generate. Through these efforts, you will create the data foundation for our work in imaging science.

You will help manage all the data pipeline needs for our platforms, CELLxGENE Discover, CryoET, as well as the new platform we are building that has a focus on data for AI and the virtual cell. This would include data ingestion, validation, and transformation needs in order to enable scientists to further interrogate our very large and growing corpus of data.

The Team CZI supports the science and technology that will make it possible to help scientists cure, prevent, or manage all diseases by the end of this century. While this may seem like an audacious goal, in the last 100 years, biomedical science has made tremendous strides in understanding biological systems, advancing human health, and treating disease. Achieving our mission will only be possible if scientists are able to better understand human biology. To that end, we have identified four grand challenges that will unlock the mysteries of the cell and how cells interact within systems — paving the way for new discoveries that will change medicine in the decades that follow: Building an AI-based virtual cell model to predict and understand cellular behavior Developing state-of-the-art imaging systems to observe living cells in action Instrumenting tissues to better understand inflammation, a key driver of many diseases Engineering and harnessing the immune system for early detection, prevention, and treatment of disease CZI’s work in science includes grantmaking programs, open-source software development, and close collaboration with the Chan Zuckerberg Biohub Network. The CZ Biohub Network includes the San Francisco, Chicago, and New York Biohubs as well as the Chan Zuckerberg Imaging Institute. CZI also collaborates with institutional partners like the Kempner Institute for the Study of Natural & Artificial Intelligence at Harvard University. Join us in accelerating science. The Opportunity We are seeking a Senior Product Manager with deep expertise at the intersection of artificial intelligence and biology. In this role, you will lead the development of innovative products that apply state-of-the-art AI to accelerate biological research. As part of the Science Technology (SciTech) team, you will shape products that empower both computational and experimental researchers to use AI for in silico experimentation, hypothesis generation, data interpretation, and biological modeling. You will work across disciplines to identify high-impact opportunities where AI can meaningfully accelerate scientific progress, and translate them into impactful, scalable tools integrated within the CZI Virtual Cells Platform. Examples include: Multi-modal workflows for users to run inference on models using their own data for key tasks like data annotation and comparing data to a reference (e.g. healthy vs disease). Tools that enable researchers to run and visualize in silico experiments using AI models, e.g. simulate how specific gene knockouts affect cell behavior in a virtual T-cell model. AI agents that assist experimental biologists in designing experiments by integrating prior datasets, model predictions, and literature insights.

You will be responsible for shaping and supporting an internal communications program that informs, engages, and inspires employees by bringing CZI’s mission and work to life, fostering a clear understanding of CZI’s strategies across our science and education efforts, and advising the leadership team on messaging and delivery.

You will be responsible for maintaining and optimizing the building infrastructure and laboratory equipment in a cutting-edge scientific research institute, and ensuring compliance with strict regulations and proper functionality of critical systems like HVAC, electrical, and other utilities while supporting research and production operations safely and efficiently.

You will manage a team of data scientists who are embedded in cross-functional, AI-modeling focused teams and are responsible for leading dataset definition and delivery to support modeling work. Success is measured by the speed with which datasets are available, the ease with which they can be used, the suitability of the dataset to address the modeling task, and the clarity with which data quality is available to the research team. As a manager of a small team, this role will be a player/coach position. Your individual contributions will focus on defining a strategic, integrated dataset design sufficient to realize a Virtual Cell Model, and to ensure that the individual datasets your team creates for each modeling project each create measurable progress towards the integrated design.

The Team Across our work in Science, Education, and within our communities, we pair technology with grantmaking, impact investing, and collaboration to help accelerate the pace of progress toward our mission. Our Central Operations & Partners team provides the support needed to push this work forward. Central Operations & Partners consists of our Brand & Communications, Community, Facilities, Finance, Infrastructure/IT Operations/Business Systems, Initiative Operations, People, Real Estate/Workplace/Facilities/Security, Research & Learning, and Ventures teams. These teams provide the essential operations, services, and strategies needed to support CZI’s progress toward achieving its mission to build a better future for everyone. Our Central Tech team provides technology and security support for CZI and our grantees. We believe that Engineering, IT and Security are most effective when in sync and learning from each other on a daily basis. Across our three pillars of Infrastructure, Security, and Grantee & Partner Support, we enable our teams to achieve their goals faster and more securely. We leverage technology to automate manual processes, constantly innovate to optimize operations, provide first-class support, and build solutions to enable the scale and execution of our business partners' strategies and initiatives. The Opportunity We are seeking a visionary and experienced Senior Manager to lead our End User Support team. This is a high-impact leadership role that requires both strategic foresight and hands-on execution. You will be responsible for shaping the future of end-user service delivery at CZI—defining what exceptional support looks like and building the systems, team, and culture to achieve it. You’ll lead a high-performing team that supports a diverse and distributed workforce, ensuring seamless and secure access to the tools and services employees need to thrive. Your leadership will help transform support into a proactive, data-driven, and automation-enabled function that scales with CZI’s growing needs.

You will lead full-cycle recruiting across Operations, partnering with leaders to hire exceptional talent from early career to executive level. Join a collaborative team that values fresh ideas and a relentless focus on delivering a best-in-class candidate experience.